The Italian striker is expected to make an announcement on his future.
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Bologna's captain will meet the press on Friday at 12:45 pm local time (8:45 am ET) at the club's Casteldebole training complex.
"I believe Marco will announce he is leaving Bologna", La Repubblica reporter Francesco Intorcia told SoccerPlus on Thursday.
On Wednesday, France Football corroborated this site's report that an agreement in principle has been reached that will bring Di Vaio to the North American top flight next month, adding the deal will be a free transfer, since the Italian's current contract goes until June 2013.
Bologna is playing its final home game on Sunday against Napoli and will have a final match to play on May 13 in Parma. Wednesday, Di Vaio was used as a late sub in a 1-0 win at Catania.
Do not miss a special edition of SoccerPlus Extra on Friday with all the details from the press conference in Italy, also available on the iTunes Store and on Stitcher (www.stitcher.com) your source of information for on demand audio content.