Deputizing in net will be either Quillan Roberts or Alex Bono, who took over the gloves on Saturday in Florida and was helpless as Kaka’s injury time penalty sent TFC home empty handed. Irwin has played every game to date in his debut season in Toronto since making the move from Colorado Rapids.
Toronto will also be without club captain Michael Bradley, who has returned from U.S. national team duty at the Copa America with an apparent leg injury.
The Reds haven’t tasted success in the tournament since 2012 while Vancouver will seek to retain the silverwear they won last season.
Sebastian Giovinco scored the solidarity goal in the first leg at BMO Field last week, when Toronto bossed the midfield, Benoit Cheyrou with another standout performance.
The Whitecaps, 7-7-3 in MLS, secured an impressive 3-2 road victory against the Eastern Conference pacesetters Philadelphia Union on Saturday.
However, the big news out of Vancouver is that Octavio Rivero’s appearance at BMO was his last in a Whitecaps uniform. The DP striker is on the move to Colo-Colo in Chile. Erik Hurtado replaced him at the point of the attack against Philadelphia and midfielders Kekuta Manneh and Christian Bolaños stepped up with a goal apiece.
TFC’s Josh Williams is eligible for cup play despite being sent off late for protesting the award of the late Orlando penalty on Saturday but Eriq Zavaleta may come back in to partner Drew Moor in a backline that will seek to limit pressure on their rookie goalie.
The Voyageurs Cup winner is awarded Canada's lone spot in CONCACAF Champions League.
Toronto: A.Bono, N.Hagglund, E.Zavaleta, D.Moor, J.Morrow B.Cheyrou, W.Johnson, J.Osorio, S.Giovinco, M.Babouli, J.Hamilton
Vancouver: D.Ousted, J.Smith, A.Jacobson, T.Parker, J.Harvey, P.Morales, M.Laba, N.Mezquida, C.Bolanos, K.Manneh, E.Hurtado
Broadcast: TSN, TSN 1410